A Randomized Phase II Trial of White Button Mushroom in Patients with Biochemically Recurrent Prostate Cancer Following Local Therapy and in Therapy Naïve Patients with Favorable Risk Prostate Cancer undergoing Active Surveillance.
This phase II trial studies how well white button mushroom supplement works in reducing prostate-specific antigen (PSA) levels in patients with prostate cancer that has come back (recurrent) or has favorable risk and has not undergone any therapy (therapy naive). PSA is a blood marker of prostate growth. White button mushroom supplement may affect PSA level, various parameters of immune system and levels of hormones that may have a role in prostate cancer growth.
No prior treatment with PARP inhibitor, cyclophosphamide, or mitoxantrone chemo. Bilateral orchiectomy or ongoing androgen deprivation therapy with GnRH. agonist/antagonist