CSMC IRB No: SITE00000136
CSMC Date Effective: 3/5/2024

DIET2TREAT Study

A Randomized Study of the Ketogenic Diet versus Standard Dietary Guidance for Patients with Newly Diagnosed Glioblastoma

Saint John’s Cancer Institute is seeking participants for a clinical trial that will explore the use of a ketogenic diet vs standard dietary guidance and how it impacts glioblastoma survival.

To be eligible for this study, you must be:
• Age ≥ 18 years
• Newly diagnosed with glioblastoma (within two months of initial diagnosis by histopathology)
• Not started standard-of-care chemotherapy and/or radiation therapy
• Able to read, write, and understand either English or Spanish
• Have a smart device (like a smartphone or tablet) that can download and run apps

If you are eligible and choose to participate, you will be asked to:

• Meet with a study dietitian every two weeks for 18 weeks
• Be prepared to adjust your diet to align with the dietitian’s advice
• Complete questionnaires and give additional blood and stool samples
• Wear a Fitbit for 18 weeks (provided by the study)
• If you are part of the Keto Diet group, you will be asked to take daily glucose measurements using
the Keto-Mojo device (provided by the study)

Principal Investigator
Akanksha Sharma, MD

For more information, contact the Neuro-Oncology Clinical Trial Team
Neuro.Oncology@providence.org
310-829-8265

Sponsor
Cedars-Sinai Medical Center

Download the Flyer (PDF)