{"id":2497,"date":"2022-08-10T21:51:14","date_gmt":"2022-08-10T21:51:14","guid":{"rendered":"https:\/\/www.saintjohnscancer.org\/blog\/?p=2497"},"modified":"2022-09-16T17:06:03","modified_gmt":"2022-09-16T17:06:03","slug":"a-quarter-of-century-later-john-santoliquido-is-cancer-free-of-metastatic-melanoma","status":"publish","type":"post","link":"https:\/\/www.saintjohnscancer.org\/blog\/melanoma\/a-quarter-of-century-later-john-santoliquido-is-cancer-free-of-metastatic-melanoma\/","title":{"rendered":"A Quarter Century Later, Metastatic Melanoma Patient is Still Cancer Free"},"content":{"rendered":"\n<h2>Diagnosed in 1997 under the late Donald Morton, MD, and attending physician Richard Essner, MD, John refuses to see anyone else when it comes to his Stage 4 cancer treatments.<\/h2>\n<p><span data-contrast=\"auto\">Meet John Santoliquido; an extraordinary man whose keen love of life found himself advocating for nothing less than the life he wanted. <\/span><\/p>\n<p><span data-contrast=\"auto\">John&rsquo;s care team was comprised of the late <a href=\"https:\/\/www.saintjohnscancer.org\/about-us\/oncology-visionary-donald-l-morton-md\/\">Donald L. Morton, MD<\/a>, whose legacy pioneered the sentinel lymph node biopsy, which projected the Cancer Institute amongst the best in the nation for melanoma cancer care, and <a href=\"https:\/\/www.saintjohnscancer.org\/about-us\/people\/richard-essner-m-d\/\">Richard Essner, MD<\/a>, a peer of Dr. Morton&rsquo;s, and now program co-director of the Melanoma, Skin and Soft Tissue center of excellence at Saint John&rsquo;s Cancer Institute. John purportedly remained a patient of Dr. Essner even while Dr. Essner made a switch to Cedars-Sinai, and when Dr. Essner returned to Saint John&rsquo;s Health Center to become the program director, John did as well. &ldquo;<span class=\"NormalTextRun AdvancedProofingIssueV2Themed SCXW167216377 BCX8\">It&rsquo;s<\/span><span class=\"NormalTextRun SCXW167216377 BCX8\"> just nice being back here at this location because it really is a whole group working together for my best outcome,&rdquo; John explains in his video vignette (below).&nbsp;<\/span><\/span><\/p>\n<div style=\"text-align: center;padding-bottom: 40px\">\n<blockquote><p><span style=\"letter-spacing: -1px\">John Santoliquido has been cancer-free for 25-years of stage 4 metastatic melanoma.<\/span><\/p><\/blockquote>\n<\/div>\n<h3>Listen to John tell his story<\/h3>\n<p><iframe loading=\"lazy\" title=\"Stage 4B Metastatic Melanoma Cancer Survivor, John Santoliquido shares his experience after 25 Years\" width=\"912\" height=\"513\" src=\"https:\/\/www.youtube.com\/embed\/n2CW_vpFZWc?rel=0&amp;showinfo=0\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<div style=\"text-align: center;padding-left: 10%;padding-right: 10%\" align=\"center\">\n<p style=\"text-align: center;font-size: 14px;line-height: 14px;margin-top: 15px;color: #808080;padding-bottom: 25px!important\">John shares his experience with Saint John&rsquo;s Cancer Institute in Santa Monica, California.<\/p>\n<\/div>\n<h3><span data-contrast=\"auto\">What is a slow-growing cancer? <\/span><span data-ccp-props='{\"201341983\":0,\"335559739\":160,\"335559740\":259}'>&nbsp;<\/span><\/h3>\n<p style=\"text-align: left\"><span data-contrast=\"auto\">&ldquo;There is no precise way to measure the rate of growth of metastatic melanoma,&rdquo; explains <a href=\"https:\/\/www.saintjohnscancer.org\/about-us\/people\/kim-margolin\/\">Dr. Kim Margolin<\/a>. &nbsp;&ldquo;We just use terms like that when it seems like a very long time between one crop of metastases and the next one.&rdquo; In John&rsquo;s case, it would take another 20 years for a metastasis to appear and in his right lung. More frequently than not, m<\/span><span data-ccp-props='{\"201341983\":0,\"335559739\":160,\"335559740\":259}'>elanoma is an aggressive cancer, and once in the bloodstream may spread to places in the body, asymptomatically.&nbsp;<\/span><\/p>\n<p style=\"text-align: left\"><span data-contrast=\"auto\">Dr. Margolin attributes John&rsquo;s long survival to his immunity for being, &ldquo;unusually strong against melanoma antigens.&rdquo; Statistically, 30 percent of patients with metastatic melanoma make it to the 5-year benchmark<\/span><span data-ccp-props='{\"201341983\":0,\"335559739\":160,\"335559740\":259}'>. <\/span><\/p>\n<p style=\"text-align: left\"><span data-ccp-props='{\"201341983\":0,\"335559739\":160,\"335559740\":259}'>Unique to John, is his ability to speak to the steady and improved progression in medical treatments over the past quarter century, and participated in some clinical trials, as a result.<\/span><\/p>\n<h3>How immunotherapy treatment for metastatic melanoma cancer improved over Time.<\/h3>\n<p style=\"text-align: left\"><span data-contrast=\"auto\">John&rsquo;s cancer first appeared in his groan in 1997. It was soon realized that the primary tumor originated in his left calf and his diagnosis went from stage 2 to stage 4 (<a href=\"https:\/\/www.saintjohnscancer.org\/melanoma\/conditions\/melanoma\/\">see staging<\/a>). Treatment in the 90s included irradiating melanoma with TB (tuberculosis) and then injecting it into the affected areas, in this case, John&rsquo;s groan and left armpit areas. He was then put on an immunotherapy treatment called alpha interferon, where John had to self-inject three times a week, &ldquo;it was awful,&rdquo; he reports. An immunotherapy treatment that later was done away with, &ldquo;it was a very weak, very toxic immunotherapy,&rdquo; according to Dr. Margolin, medical oncologist and co-director for Melanoma, Skin and Soft Tissue Tumors program at Saint John&rsquo;s Cancer Institute. <\/span><span data-ccp-props='{\"201341983\":0,\"335559739\":160,\"335559740\":259}'>&nbsp;<\/span><\/p>\n<p><span data-contrast=\"auto\">Immunotherapy aids the body to fight cancer by utilizing the body&rsquo;s own immunity to fight and target cancer cells. In 2014, a new immunotherapy treatment became available called, OPDIVO, which has revolutionized effectiveness and outcomes, especially with regard to advanced melanoma.&nbsp;<\/span><\/p>\n<div style=\"text-align: center;padding-bottom: 40px\">\n<blockquote><p><span style=\"letter-spacing: -1px\">Melanoma tricks the immune system to <em>not<\/em> fight cancer, because the body doesn&rsquo;t know it is cancer.<\/span><\/p><\/blockquote>\n<\/div>\n<p><span data-contrast=\"auto\">In 2018, John&rsquo;s cancer came back in his right lung, and was put on OPDIVO for one year. He reports in his testimonial the difference in symptoms, and side effects&ndash;to which were mild to none in comparison to it&rsquo;s predecessor. <\/span><\/p>\n<p><span data-contrast=\"auto\">Currently, John is not taking immunotherapy, but continues to come for his yearly exams.&nbsp;<\/span><\/p>\n<h3>Advise for those going through treatment today<\/h3>\n<p style=\"text-align: left\"><span data-contrast=\"auto\">Because John did not want his lifestyle to change, and he knew chemotherapy treatment would impact him, he questioned his care team for an alternative care path. He attributes his long life to pursuing other treatment options, i.e. immunotherapy, and to the doctors for seriously considering his needs. <\/span><span data-contrast=\"auto\">&ldquo;They have kept me alive since 1997, so I put my life in their hands at anytime,&rdquo;<\/span><span data-ccp-props='{\"201341983\":0,\"335559739\":160,\"335559740\":259}'> remarks John.<\/span><\/p>\n<div style=\"text-align: center;padding-bottom: 40px\">\n<blockquote><p><span style=\"letter-spacing: -1px\">You have to be your own advocate as far as asking all the questions you can.<\/span><\/p><\/blockquote>\n<\/div>\n<h4>Save the date: Melanoma, Soft and Skin Tissues upcoming events<\/h4>\n<p><em>Santa Monica Melanoma Symposium<\/em> is a CME event for professionals seeking to learn from the nation&rsquo;s experts on Melanoma and cutaneous oncology. The next Melanoma Symposium will be held in May 2023. Follow @santamonicamelanomasymposium on Instagram to learn more.<\/p>\n<p>A patient Melanoma Symposium will be held on October 29, 2022, for patients seeking answers. This event is generously being sponsored by AIM. Stay tuned for more venue specifics.<\/p>\n\n","protected":false},"excerpt":{"rendered":"<p>Diagnosed in 1997 under the late Donald Morton, MD, and attending physician Richard Essner, MD, John refuses to see anyone&#8230;<\/p>\n","protected":false},"author":63,"featured_media":2499,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[138],"tags":[],"class_list":["post-2497","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-melanoma"],"acf":{"doc_author":"0","header_scripts":""},"_links":{"self":[{"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/posts\/2497","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/users\/63"}],"replies":[{"embeddable":true,"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/comments?post=2497"}],"version-history":[{"count":0,"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/posts\/2497\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/media\/2499"}],"wp:attachment":[{"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/media?parent=2497"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/categories?post=2497"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.saintjohnscancer.org\/blog\/wp-json\/wp\/v2\/tags?post=2497"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}