A Retrospective Study Observational Study for H3 K27M-nutenat and/or Midline Gliomas

There is limited published information about prognostic factors and the progression of H3 K27M-mutant glioma. Therefore, this natural history study aims to better define the response to treatment, natural disease progression, outcomes, and prognostic factors in patients with H3 K27M-mutant and/or midline glioma. Furthermore, this study will provide contextual data for the ONC201 clinical development program.

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