Translational Research
Translational Research 310-449-5267
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      • Blood Biopsy
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      • Urology: Assessment of Robotic Surgical Procedures & CFNA in Urine
      • Assessment of Primary Brain Tumor & Solid Tumor Metastasis Genetics and Cancer Epigenetics Pathways
      • Monitoring Blood of Melanoma Patients Receiving CheckPoint Inhibitor Immunotherapy
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      • RNA Splicing Regulation of Immune Response in Triple-Negative Breast Cancer
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Current Research Topics

Contact Our Research Departments Coronavirus (COVID-19) Advisory: Please help us limit exposure. Learn more about COVID-19 and where to go if you have concerns.
Current Research Topics Contact Our Research Departments Coronavirus (COVID-19) Advisory: Please help us limit exposure. Learn more about COVID-19 and where to go if you have concerns.
Molecular Medicine Current Research Topics

Blood Biopsy

Dr. Hoon and his team have discovered and established various types of blood biopsy biomarker panels for disease monitoring including isolating, profiling and characterizing blood and urine cfDNAs using contemporary technologies such as next-generation sequencing (NGS) and droplet digital PCR (ddPCR).

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Oncogenic Pathways Involved in Chemoresistance & Progression of Solid Tumors

Our goal is to identify pathways aberrantly expressed in different tumors types (cutaneous melanoma, breast cancer, esophageal squamous cell carcinoma, gastrointestinal tumors, and gliomas) driving progression and resistant to current therapies.

Learn More

Urology: Assessment of Robotic Surgical Procedures & CFNA in Urine

The Urology clinical research program has many ongoing translational molecular oncology studies involving various cancer types: prostate, bladder and kidney cancer.

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Assessment of Primary Brain Tumor & Solid Tumor Metastasis Genetics and Cancer Epigenetics Pathways

Our research studies are focused on gliomas and melanoma brain metastasis (MBM).

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Monitoring Blood of Melanoma Patients Receiving CheckPoint Inhibitor Immunotherapy

Assessment of melanoma patients receiving CII through assessing CTC and cfNA to assess multimodality treatments in blood and urine of melanoma patients.

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Monitoring Metastatic Breast Cancer Patients Receiving Standard Chemotherapies

A blood and urine cfDNA methylation assay for breast cancer prognosis prediction and treatment monitoring.

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Evaluating Ovarian Cancer Patients

Evaluating blood and urine using cfNA assays for monitoring tumor progression.

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Next Generation Sequencing

From library preparation to producing high quality sequencing data, we offer a variety of sequencing services to meet today’s fast-paced research environment.

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Specimen Repository

We maintain a unique bank of frozen or paraffin-embedded melanoma specimens collected since 1971.

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About Saint John’s Cancer Institute

Saint John’s Cancer Institute is a cancer research institute dedicated to the understanding and curing of cancer in order to eliminate patient suffering worldwide.

Administrative Office & Research Center:
2200 Santa Monica Blvd.
Santa Monica, CA 90404
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Providence Saint John’s Health Center
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