Current Research Topics

Dr. Hoon and his team have discovered and established various types of blood biopsy biomarker panels for disease monitoring including isolating, profiling and characterizing blood and urine cfDNAs using contemporary technologies such as next-generation sequencing (NGS) and droplet digital PCR (ddPCR).

Our goal is to identify pathways aberrantly expressed in different tumors types (cutaneous melanoma, breast cancer, esophageal squamous cell carcinoma, gastrointestinal tumors, and gliomas) driving progression and resistant to current therapies.

The Urology clinical research program has many ongoing translational molecular oncology studies involving various cancer types: prostate, bladder and kidney cancer.

Our research studies are focused on gliomas and melanoma brain metastasis (MBM).

Assessment of melanoma patients receiving CII through assessing CTC and cfNA to assess multimodality treatments in blood and urine of melanoma patients.

A blood and urine cfDNA methylation assay for breast cancer prognosis prediction and treatment monitoring.

Evaluating blood and urine using cfNA assays for monitoring tumor progression.

From library preparation to producing high quality sequencing data, we offer a variety of sequencing services to meet today’s fast-paced research environment.

We maintain a unique bank of frozen or paraffin-embedded melanoma specimens collected since 1971.