Blood Biopsy: CTC, cfDNA, MicroRNA

Dr. Dave Hoon has been one of the pioneers in the blood molecular biopsy field since 1991. For the past 25 years, Dr. Hoon has devoted to studying cfNA and CTC present in the body fluid, and has published substantial high impact scientific reports. Throughout this time, Dr. Hoon and his team have discovered/uncovered and established various types of blood biopsy biomarker panels for disease monitoring. These include genetic mutations, copy number variations (CNVs), DNA methylations, and microRNA signatures in multiple solid tumor cancer types. Dr. Hoon has also participated in multiple phase II and III clinical trials (in both domestic and international settings) to evaluate new treatment approaches for early stage and advanced stage patients.

Dr. Hoon is also in collaboration with institutes worldwide to help develop new approaches in this field. He has been on the executive board member of the European Cancer-ID program, and is an active scientific advisor and board member of many pharmabiotech companies.

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CFNA Program

  • Dr. Hoon’s lab has expertise in isolating, profiling and characterizing blood and urine cfDNAs using contemporary technologies such as next-generation sequencing (NGS) and droplet digital PCR (ddPCR), thus providing strong assistance for the clinicians at the JWCI for disease early detection, recurrence prediction, and therapeutic guidance.
  • Dr. Hoon’s current research is focused on developing new approaches for processing blood and urine biopsies, and validating known biomarker panels in different body fluids such as blood, urine, saliva, and breath. Dr. Hoon’s lab has special expertise in isolating, profiling and characterizing blood and urine cfDNAs and CTCs using the cutting edge technologies such as next-generation sequencing (NGS) and droplet digital PCR (ddPCR), thus providing strong assistance for the clinicians at the JWCI for disease early detection, recurrence prediction, and therapeutic guidance
JWCI Translational Molecular Medicine Researchers discussing data