SCOTT P. LAYNE, MD FACP FIDSA is a physician-scientist known for interdisciplinary work in applied virology, large-scale laboratory technologies, biological security policy, and epidemiologic analysis. He has over 60 publications (including books, patents, and government reports) with many technical publications appearing in the Proceedings of the National Academy of Science, Nature, and Science.
Throughout the pandemic, as a practicing infectious disease physician, Dr. Layne has cared for over 500 patients who were hospitalized for acute SARS-CoV-2 infections and life-threatening COVID-19. He has organized major scientific studies to understand how COVID-19 attacks and destroys human lungs and also authored major publications on topics pertaining to molecular pathogenesis of COVID-19 and needs for global surveillance of SARS-CoV-2 variants.
In January 2020, Dr. Layne warned the New Zealand Counsel-General in the United States to prepare his island nation against the looming pandemic. His advisories to New Zealand authorities prompted the initiation of science-driven containment strategies that were maintained until April 2021. Ultimately, after 15 months of maintaining a national COVID-19 free zone, increasing societal fatigue forced government ministers to open quarantine-free travel between New Zealand and Australia, which resulted in an irreversible loss of safeguards. Since January 2022, New Zealand has been hit with an exponential Omicron wave.
Dr. Scott P Layne’s strong scientific background, wide clinical experience, and high-level advisory roles have shaped his perspectives on the need for longer-lasting, broader acting, and variant resistant COVID-19 vaccines that are available worldwide. To fulfill these aims, he conceived and organized the Prospective Boost and Evaluation Study of COVID-19 (PROBES19) and will serve as the principal investigator of this groundbreaking effort.
Pandemic Related Publications
- Science Translational Medicine. New coronavirus outbreak: Framing questions for pandemic prevention. March 11, 2020.
- Science Translational Medicine. Increasing threats from SARS-CoV-2 variants: Time to establish global surveillance. July 7, 2021.
- ThinkGlobalHealth. How to Build a Global COVID-19 Surveillance Program. July 9, 2021.
- Science Translational Medicine. Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19. October 10, 2021.
- Nature Medicine. More autopsy studies are needed to understand the pathogenesis of severe COVID-19. February 17, 2022.
View Dr. Scott Layne on LinkedIn
Education and Training
Bachelor of Arts
Chemistry, DePauw University
Medical Doctor
Case Western Reserve University
Internship
Psychiatry, Loma Linda University
Graduate Study
Applied Physics, Stanford University
Residency
Internal Medicine, UCLA Department of Medicine
Fellowship
(Adult) Infectious Diseases, UCLA Department of Medicine
Medical Certifications
- 1981 – now Diplomat, National Board of Medical Examiners
- 1981 – now Medical License, California
- 1983 – now Medical License, New Mexico
- 1997 – 2007 Certified, Internal Medicine, American Board of Internal Medicine
- 1998 – 2008 Certified, Infectious Diseases (Adult), American Board of Internal Medicine
- 2011 – 2021 Certified, Infectious Diseases (Adult), American Board of Internal Medicine
- 2015 – 2021 Certified, Internal Medicine, National Board of Physicians and Surgeons
- 2015 – 2021 Certified, Infectious Diseases (Adult), National Board of Physicians and Surgeons
Active Hospital Privileges
- 2005 – now Providence Saint John’s Health Center
- 2005 – now Santa Monica UCLA Medical Center
- 2005 – now Cedars-Sinai Marina Del Rey Hospital
- 2005 – now Kindred Hospital Los Angeles
- 2014 – now Centinela Hospital
- 2015 – now Cedars-Sinai Medical Center
Honors and Fellowships
- 1976 Phi Beta Kappa, DePauw University
- 1976 Rhodes Scholarship Candidate, DePauw University
- 1996 Delta Omega
- 2013 Fellow, American College of Physicians (FACP)
- 2014 Fellow, Infectious Diseases Society of America (FIDSA)
Memberships
- 1992 American Society for Microbiology
- 2001 Infectious Disease Society of America
- 2001 Infectious Disease Association of California
- 2004 American College of Physicians
- 2013 California Medical Association
Peer-reviewed Publications
- Peter S. Lomdahl, Scott P. Layne, Irving J. Bigio. Solitons in Biology. Los Alamos Science 10, 2 – 22 (1984).
- Scott P. Layne. A Possible Mechanism for General Anesthesia. Los Alamos Science 10, 23 – 26 (1984).
- Harvey J. Wasserman, Robert R. Ryan, Scott P. Layne. Structure of Acetanilide at 113 K. Acta Cryst. C41, 783 – 785 (1985).
- Scott P. Layne, Irving J. Bigio, Alwyn C. Scott, Peter S. Lomdahl. Transient Fluorescence in Synchronously Dividing Escherichia coli. Proc. Natl. Acad. Sci. USA 82, 7599 – 7603 (1985).
- Scott P. Layne, I. J. Bigio. Raman Spectroscopy of Bacillus Megaterium Using an Optical Multi-Channel Analyzer. Physica Scripta 33, 91 – 96 (1986).
- Gottfried Mayer-Kress, Scott P. Layne. Dimensionality of the Human Electro-encephalogram. Ann. N. Y. Acad. Sci. 504, 62 – 87 (1987).
- Scott P. Layne, Thomas G. Marr, Stirling A. Colgate, James M. Hyman, E. Ann Stanley. The Need for National HIV Databases. Nature 333, 511 – 512 (1988).
- Stirling A. Colgate, E. Ann Stanley, James M. Hyman, Scott P. Layne, Clifford R. Qualls. Risk Behavior-Based Model of the Cubic Growth of Acquired Immunodeficiency Syndrome in the United States. Proc. Natl. Acad. Sci. USA 86, 4793 – 4797 (1989).
- Scott P. Layne, John L. Spouge, Micah Dembo. Quantifying the Infectivity of Human Immunodeficiency Virus. Proc. Natl. Acad. Sci. USA 86, 4644 – 4648 (1989).
- Stirling A. Colgate, E. Ann Stanley, James M. Hyman, Clifford R. Qualls, Scott P. Layne. AIDS and a risk-based model. Los Alamos Science 18, 2 – 23 (1989).
- Scott P. Layne, Micah Dembo, John L. Spouge. The Kinetics of HIV Infectivity. Los Alamos Science 18, 91 – 109 (1989).
- John L. Spouge, Scott P. Layne, Micah Dembo. Analytic Results for Quantifying HIV Infectivity. Bull. Math. Biol. 51, 715 – 730 (1989).
- Scott P. Layne, John L. Spouge, Micah Dembo. Measuring HIV Infectivity. Lecture Notes in Biomathematics 83, 80 – 110 (1989).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Peter L. Nara. HIV Requires Multiple gp120 Molecules for CD4-Mediated Infection. Nature 346, 277 – 279 (1990).
- Scott P. Layne, Michael J. Merges, John L. Spouge, Micah Dembo, Peter L. Nara. Blocking of HIV Infection Depends on Cell Density and Viral Stock Age. J. Virology 65, 3293 – 3300 (1991).
- Scott P. Layne, Micah Dembo. The Auto-Regulation Model: A Unified Concept of How HIV Regulates its Infectivity, Pathogenesis and Persistence. International Reviews of Immunology 8, 1 – 32 (1992).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Shawn R. Conley, John P. Moore, Jawahar L. Raina, Herbert Renz, Hans R. Gelderblom, Peter L. Nara. Factors Underlying Spontaneous Inactivation and Susceptibility to Neutralization of Human Immunodeficiency Virus. Virology 189, 695 – 714 (1992).
- Scott P. Layne, Tony J. Beugelsdijk. Laboratory Firepower for Infectious Disease Research. Nature Biotechnology 16, 825 – 829 (1998).
- Scott P. Layne, Tony J. Beugelsdijk. Mass Customized Testing and Manufacturing via the Internet. Robotics and Computer-Integrated Manufacturing 14, 377 – 387 (1998).
- John L. Spouge, Scott P. Layne. A Practical Method for Simultaneously Determining the Effective Burst Sizes and Cycle Times of Viruses. Proc. Natl. Acad. Sci. USA 96, 7017 – 7022 (1999).
- Jeffery K. Taubenberger, Scott P. Layne. Diagnosis of Influenza Virus: Coming to Grips with the Molecular Era. Journal Molecular Diseases 6, 291 – 305 (2001).
- Scott P. Layne, Tony J. Beugelsdijk. High-Throughput Laboratories for Homeland and National Security. Biosecurity and Bioterrorism 1, 123 – 130 (2003).
- Tony J. Beugelsdijk, Scott P. Layne. The Role of High-Throughput Laboratories in Homeland Security. Journal Association Laboratory Automation 8(5), 11 – 18 (2003).
- Scott P. Layne. Human Influenza Surveillance: the Demand to Expand. Emerging Infectious Diseases 12, 562 – 569 (2006).
- Emily Kajita, Justin Okano, Erin N. Bodine, Scott P. Layne, Sally Blower. Modeling an outbreak of an emerging pathogen. Nature Reviews Microbiology 5, 1 – 10 (2007).
- Scott P. Layne, Arnold S. Monto, Jeffrey K. Taubenberger. Pandemic Influenza: An Inconvenient Mutation. Science 323, 1560 – 1561 (2009).
- Scott P. Layne, James M. Hyman, David M. Morens, Jeffrey K. Taubenberger. New coronavirus outbreak: Framing questions for pandemic prevention. Science Translational Medicine 12(534) eabb1469 (2020).
- Joseph M. Rosen, Lisa V. Adams, Scott P. Layne, Eliot B. Grigg, Christian R. Macedonia, Robyn E. Mosher, Kendra A. Hebert, Jacob C. Jurmain, Luis Kun. Cybercare 3.0: Using Innovative Technology to Provide Hospital Care to COVID-19 Patients in the Home. IEEE Translational Engineering in Health and Medicine. To appear (2020).
Pandemic-related Publications
- Science Translational Medicine. New coronavirus outbreak: Framing questions for pandemic prevention. March 11, 2020.
- Science Translational Medicine. Increasing threats from SARS-CoV-2 variants: Time to establish global surveillance. July 7, 2021.
- ThinkGlobalHealth. How to Build a Global COVID-19 Surveillance Program. July 9, 2021.
- Science Translational Medicine. Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19. October 10, 2021.
- Nature Medicine. More autopsy studies are needed to understand the pathogenesis of severe COVID-19. February 17, 2022.
Patents
- Scott P. Layne, Tony J. Beugelsdijk. Method and Apparatus for Globally-Accessible Automated Testing. U.S. Patent Number 5,841,975 (1998).
- Scott P. Layne, Tony J. Beugelsdijk. Apparatus for Testing for Infection by a Retrovirus. U.S. Patent Number 5,925,514 (1999).
- Scott P. Layne, Tony J. Beugelsdijk. Apparatus for Automated Testing of Biological Specimens. U.S. Patent Number 5,968,731 (1999).
- Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee. Monoliths. U.S. Patent Number 9,464,969 B2 (2016).
- Mark A. Dobbs, Scott P. Layne, Milton Lee, Keith A. Oberg, Ekaterina Tkatchouk. Monoliths. Australia Patent Number 2014412015B2 (2016).
- Mark A. Dobbs, Scott P. Layne, Milton Lee, Keith A. Oberg, Ekaterina Tkatchouk. Monoliths. AU2014412015B2 (2019).
Book Chapters
- Scott P. Layne, Alwyn C. Scott. A Hypothesis of Barbiturate Action Mediated Via Membrane and Cytoskeletal Proteins. in The Neurobiology of Pain (editors A. V. Holden, W. Winlow). Manchester University Press, 309 – 335 (1984).
- Scott P. Layne. The Modification of Davydov Solitons by The Extrinsic H-N-C=O Group. in Nonlinear Electrodynamics in Biological Systems (W. R. Adey, A. F. Lawrence, editors). Plenum Press, 531 – 548 (1984).
- James A. Krumhansl, Gary M. Wysin, Denise M. Alexander, Angel Garcia, Peter S. Lomdahl, Scott P. Layne. Further Theoretical Studies of (Nonlinear) Conformational Motions in Double-Helix DNA. in Structure and Motion: Membranes, Nucleic Acids and Proteins (E. Clementi, G. Corongiu, M. H. Sarma, R. H. Sarma, editors). Adenine Press, 407-416 (1985).
- Irving J. Bigio, Clifford T. Johnston, Scott P. Layne. Experiments for the Detection of Solitons in Biopolymers. in Dynamical Problems in Soliton Systems (S. Takeno, editor). Springer-Verlag Press, 236-241 (1985).
- Scott P. Layne, Gottfried Mayer-Kress, Joachim Holzfuss. Problems with the Dimensional Analysis of Electroencephalogram Data. in Dimensions and Entropies in Chaotic Systems (G. Mayer-Kress, editor). Springer-Verlag Press, 246 – 256 (1986).
- Scott P. Layne. Raman Activity in Synchronously Dividing Bacteria? in Computer Analysis for Life Science (A. R. Bishop, C. Kawabata, editors). Ohmsha Press, 279 – 287 (1986).
- Scott P. Layne, Tony J. Beugelsdijk. Laboratory Firepower for AIDS Research. in Firepower in the Lab: Automation in the Fight Against Infectious Diseases and Bioterrorism. Washington, DC: Joseph Henry Press, 61 – 91 (2001).
- Scott P. Layne, Tony J. Beugelsdijk, Kumar Patel. Tackling Grand Challenges with Powerful Technologies. in Firepower in the Lab: Automation in the Fight Against Infectious Diseases and Bioterrorism. Washington, DC: Joseph Henry Press, 5 – 28 (2001).
- Scott P. Layne. Virtually Assured Detection and Response: Utilizing Science, Technology, and Policy Against Bioterrorism. in Biological Threats and Terrorism: Assessing the Science and Response Capabilities, Board on Global Health, Institute of Medicine. Washington, DC: National Academy Press, 211 – 217 (2002).
- Scott P. Layne. The Technical Policy Connection. in The Office of Science and Technology Policy Blue Ribbon Panel on the Threat of Biological Terrorism Directed Against Livestock (T. K. Kelly, P. Chalk, J. Bonomo, J. Parachini, B. A. Jackson, G. Cecchine, editors). Santa Monica, CA: RAND Corporation, 153 – 164 (2004).
- Scott P. Layne. Public Health and Medical Responses. in Counterterrorism: Bridging Operations and Theory (R. J. Bunker, J. P. Sullivan, B. M. Jenkins, M Devost, J T. Kirkhope, editors). Bloomington, IN: iUniverse, 320 – 324 (2015).
Books, Reports
- Scott P. Layne (editor). A National Effort to Model AIDS Epidemiology: Report of a Workshop Held at Leesburg, Virginia, July 25 – 29, 1988. Office of Science and Technology Policy, Executive Office of the President, Washington, D.C. U.S. Government Printing Office (1988).
- Scott P. Layne, Tony J. Beugelsdijk, C. Kumar N. Patel (editors). Firepower in the Lab: Automation in the Fight Against Infectious Diseases and Bioterrorism. Washington, DC: Joseph Henry Press (2001). http://www.nap.edu/catalog/9749.html
- Frederick R. Sidell, William C. Patrick, Thomas R. Dashiell, Ken Alibek, Scott Layne (editors). Jane’s Chem-Bio Handbook, Second edition. Alexandria, VA: Jane’s Information Group (2002).
- Ken Alibek, Thomas R. Dashiell, Adrian Dwyer, Scott P. Layne, William C Patrick III, John Rinard, Donald R Ponikvar and Frederick R Sidell. Jane’s Chem-Bio Handbook, Third edition. Alexandria, VA: Jane’s Information Group (2005).
Editorials
- James M. Hyman, E. Ann Stanley, Stirling A. Colgate, Scott P. Layne. Building Large-Scale Models to Understand the AIDS Epidemic. Cray Channels 10 (3), 10 – 12 (1988).
- Victor R. DeSantis, Scott P. Layne, Tony Beugelsdijk. From Conception to Construction: Establishing an Automated Laboratory from the Ground Up. Advance Laboratory 6 (7), 34 – 38 (1997).
- Kumar Patel, Tony Beugelsdijk, Scott Layne. Automation in Threat Reduction and Infectious Disease Research: Needs and New Directions. Journal of the Association for Laboratory Automation 4, 51 – 54 (1999).
- Scott P. Layne, Tony J. Beugelsdijk, C. Kumar N. Patel, Jeffery K. Taubenberger, Nancy J. Cox, Ian D. Gust, Alan J. Hay, Masato Tashiro, Daniel Lavanchy. A Global Lab Against Influenza. Science 293, 1729 (2001).
- Scott P. Layne, Claire M. Fraser. Scientific Speed is the Key in Fighting Bioterror. Los Angeles Times, May 1, page B13 (2002).
- Scott P. Layne, Michael H. Sommer. A Virus-Fed Doomsday. Los Angeles Times, October 10, page B21 (2002).
- Scott P. Layne. Put High-Tech Labs Into the Fight Against SARS and Bioterrorism. Los Angeles Times, April 4, page B17 (2003).
- Scott P. Layne. Swine Flu: Remain Vigilant. Huffington Post. Posted May 7, 2009; 10:22 AM (EST).
Abstracts, Invited Presentations
- Scott P. Layne. A Mathematical Model that Describes Protection by Soluble CD4 Protein In Vivo. 4th International AIDS Conference Abstract No. 3522, 147 (1988).
- Scott P. Layne, Thomas. G. Marr, Stirling A. Colgate, James M. Hyman, E. Ann Stanley. The Design of an HIV Database that Facilitates Data Sharing. 4th International AIDS Conference Abstract No. 4668, 228 (1988).
- E. Ann Stanley, Stirling A. Colgate, James M. Hyman, Scott P. Layne. Partner Choice in Mathematical Models for the Transmission of HIV. 4th International AIDS Conference Abstract No. 4696, 235 (1988).
- Stirling A. Colgate, James M. Hyman, E. Ann Stanley, Scott P. Layne, Clifford. R. Qualls. A Risk-based Model of the Early Growth of AIDS in the United States. 4th International AIDS Conference Abstract No. 4697, 235 (1988).
- Scott P. Layne, John L. Spouge, Micah Dembo. Quantifying HIV Infectivity. 5th International AIDS Conference Abstract No. Th.C.P.100, 633 (1989).
- Stirling A. Colgate, E. A. Stanley, James M. Hyman, Scott P. Layne, Clifford R. Qualls. A Risk Behavior Based Model of the Cubic Growth of AIDS in the United States. 5th International AIDS Conference Abstract No. T.A.O.39, 61 (1989).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Peter L. Nara. gp120 Cooperativity: A New Finding that Pertains to Vaccine Development and Receptor / Anti-Receptor Therapies. 6th International AIDS Conference Abstract No. F.A.317, 155 (1990).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Hans R. Gelderblom, Peter L. Nara. Determining Basic Molecular Requirements for Blocking Therapies and HIV Vaccines in vitro. Laboratory of Tumor Cell Biology Annual Meeting. National Institutes of Health. August 11 – 17 (1990).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Peter L. Nara. Determining Basic Molecular Requirements for Blocking Therapies and HIV Vaccines in vitro. Modern Approaches to New Vaccines Including Prevention of AIDS. Cold Spring Harbor Laboratory. September 12 – 16 (1990).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Peter L. Nara. Envelope Shedding and High Cell Density: Barriers to Vaccine and Immunotherapy Development. 7th International AIDS Conference Abstract No. M.A.1270 (1991).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Peter L. Nara. Relationships Between Envelope Shedding, Cell Density, and Humoral Blocking Activity. Laboratory of Tumor Cell Biology Annual Meeting. National Institutes of Health. September 1-8 (1991).
- Scott P. Layne, Michael J. Merges, Micah Dembo, John L. Spouge, Peter L. Nara. High physiologic cell CD4+ cell densities overcome the neutralizing activity of antibodies: A mechanism of HIV persistence. Modern Approaches to New Vaccines Including Prevention of AIDS. Cold Spring Harbor Laboratory. September 19 – 23 (1991).
- Scott P. Layne, Micah Dembo, John L. Spouge, Hans R. Gelderblom, Herbert Renz, Michael J. Merges, Peter L. Nara. Factors Regulating the Spontaneous Inactivation of HIV and its Susceptibility to Neutralization. Laboratory of Tumor Cell Biology Annual Meeting. National Institutes of Health. August 9 – 16 (1992).
- Peter L. Nara, Michael J. Merges, John L. Spouge, Shawn R. Conley, Scott P. Layne. Determinants of both Viral and Cellular Origin in Addition to the Biophysical Properties of Immunoglobulins Influence the Neutralization of HIV-1. Modern Approaches to New Vaccines Including Prevention of AIDS. Cold Spring Harbor Laboratory. September 16 – 20 (1992).
- Scott P. Layne. Evidence for the Extracellular Regulation of HIV Infection. First Annual UCLA AIDS Institute Symposium: Basic Sciences. UCLA AIDS Institute. October 27 (1992).
- Scott P. Layne, Michael J. Merges, John L. Spouge, Hans R. Gelderblom, Peter L. Nara. Extensive and Fundamental Investigations of How Humoral Immunity Blocks HIV Infection. 9th International AIDS Conference Abstract No. 996 (1993).
- John L. Spouge, Peter L. Nara, Michael J. Merges, Scott P. Layne. Viral Multiplicity of Adsorption: A Quantitative Analogue of Target-Cell Multiplicity of Infection. Laboratory of Tumor Cell Biology Annual Meeting. National Institutes of Health. August 22 – 28 (1993).
- Michael J. Merges, Scott P. Layne, John L. Spouge, Peter L. Nara. HIV-1 V3-Specific Neutralization: Valency, Reversibility, and the State of the Virion Determine In Vitro Efficacy. Laboratory of Tumor Cell Biology Annual Meeting. National Institutes of Health. August 22 – 28 (1993).
- Michael J. Merges, Scott P. Layne, John L. Spouge, Peter L. Nara. Valency, Reversibility, and the State of the Virion Determine In Vitro HIV 1 V3-Specific Neutralization Efficacy. First National Conference on Human Retroviruses and Related Infections Poster No. 71. American Society for Microbiology. December 12 – 16 (1993).
- John L. Spouge, Peter L. Nara, Michael J. Merges, Scott P. Layne. Viral Multiplicity of Attachment and its Implications for HIV Therapies. First National Conference on Human Retroviruses and Related Infections Poster No. 604. American Society for Microbiology. December 12 – 16 (1993).
- Scott P. Layne, Michael J. Merges, John L. Spouge, Peter L. Nara. Neutralization of HIV-1 by Immunoglobulin Depends on Valency and Reversibility. Annual AIDS Institute Symposium. UCLA AIDS Institute. November 11 (1994).
- Scott P. Layne, Tony J. Beugelsdijk. Automating HIV Research. University of California Directed Research and Development Activities for Fiscal Year 1996. LA-UR-97-2770 (1997).
- Scott P. Layne, Tony J. Beugelsdijk, Victor DeSantis. AIDS Research, Laboratory Automation and the Internet. Fifth Annual Bay Area Conference on Life Science Facilities. April 27 – 28 (1997).
- Scott P. Layne, Tony J. Beugelsdijk, Victor DeSantis. The UCLA – Los Alamos National Laboratory TRONLAB Program. The NASDAQ International Technology Summit. June 11 – 12 (1997).
- Scott P. Layne, Tony J. Beugelsdijk. Automating HIV Research. University of California Directed Research and Development Activities for Fiscal Year 1997. LA-UR-98-3702 (1998).
- Scott P. Layne, Tony J. Beugelsdijk. Automating HIV Research. University of California Directed Research and Development Activities for Fiscal Year 1998. LA-UR-99-3456 (1999).
- Scott P. Layne. An Overview of Emergency Response Issues. Bioterrorism: Homeland Defense Symposium. February 8 – 10 (2000).
- Scott P. Layne. High-throughput Automated Lab for Countering Bioterrorism. Bioterrorism: Homeland Defense Symposium. February 8 – 10 (2000).
- Scott P. Layne. Invited Lecture: Global Surveillance Laboratory Against Bioterrorism. Gordon Research Conference on Illicit Substance Detection. June 24 – 28 (2001).
- Scott P. Layne. Invited Lecture: Global monitoring of flu. AAAS Annual Meeting. February 14 – 19 (2002).
- Scott P. Layne. Invited Presentation: High-Speed Laboratory for Biological Security. UC System wide Bioterrorism Meeting. June 11 (2002).
- Scott P. Layne. Invited Lecture: Technological Advances in the Rapid Detection of Bioweapons and Emerging Infectious Agents. 7th Duma/NFID Annual Press Conference and Symposium of Infectious Diseases. July 18 (2002).
- Scott P. Layne. Invited Lecture: Health and Security Challenges of Bioterrorism. University of the Pacific, McGeorge School of Law Workshop: Creating a Model Syllabus for Bioterrorism and Public Health Law. March 20 – 21 (2003).
- Scott P. Layne. Invited Lecture: A New Vision of High-Throughput Labs for Homeland and National Security. Gordon Research Conference on Chemical and Biological Terrorism Defense. March 23 – 28 (2003).
- Scott P. Layne. Invited Panelist: Industrial and Government Perspectives on Influenza Control. Texas Heart Institute: 1st Symposium on Influenza and Cardiovascular Disease. April 26 (2003).
- Scott P. Layne, Eve Slater. Real-Time Global Surveillance and Analysis of Infectious Diseases with High-Throughput Laboratories Made Available via the Internet. Call for Ideas: Grand Challenges in Global Health. June 15 (2003).
- Scott P. Layne, Tony J. Beugelsdijk. High-Throughput Lab Network. August 18 (2003).
- Scott P. Layne. High-Throughput Laboratories for Biological Security. June 12 – 16 (2004).
- Scott P. Layne. A World View of Significant Infectious Diseases. November 6 (2004).
- Scott P. Layne. High-Throughput Laboratories for Biological Security: The Case for Influenza. February 3 (2005).
- Scott P. Layne. High-Throughput Laboratory Network for Influenza and Emerging Diseases. Emergence of New Epidemic Viruses through Host Switching. September 6 – 8 (2005).
- Scott P. Layne, Victor DeSantis. High-Throughput Laboratory Network. Summit on Facilities for Emerging Sciences. April 10 – 11 (2006).
- Bob Hancock, John Hepburn, Scott P. Layne, Alan Barbour, Rafick Sekaly. White Paper on Emerging Infectious Diseases. Canada-California Strategic Innovation Partnership. June 10 – 12 (2006).
- Scott P. Layne. UCLA High Speed, High Volume Laboratory Network for Infectious Diseases. Los Angeles, CA. June 29 (2006).
- Scott P. Layne, Tony J. Beugelsdijk. UCLA/LANL High Speed, High Volume Laboratory Network for Infectious Disease. Los Alamos, NM. November 2 (2006).
- Scott P. Layne. High Speed, High Volume Laboratory Network for Infectious Diseases. CNSI Membership Presentation. April 11 (2007).
- Scott P. Layne. Center for Rapid Influenza Surveillance and Research (CRISAR). NIAID Site Visit. Los Angeles, CA. April 19 (2007).
- Scott P. Layne. Center for Rapid Influenza Surveillance and Research (CRISAR). First Annual NIAID/CEIRS Meeting. Bethesda, MD. May 7 (2007).
- Scott P. Layne. UCLA High Speed, High Volume Laboratory Network for Infectious Diseases. American Society for Microbiology. Los Angeles Spring Symposium. April 21 (2007).
- Scott P. Layne, Tony J. Beugelsdijk. Technical Overview and Discussion on High-throughput systems; Laboratory methods and procedures; Containment space and configuration; Research and pandemic surge capacity modes; Information sharing and management. Scientific Advisory Board. Los Angeles, CA. April 25 (2007).
- Scott P. Layne. High-Throughput Global Lab Against Influenza. California Association of Public Health Laboratory Directors. Los Angeles, CA. October 18 (2007).
- Scott P. Layne. UCLA/LANL High Speed, High Volume Laboratory Network for Infectious Diseases. Biothreat Nonproliferation Conference. Santa Fe, NM. December 4 – 6 (2007).
- Scott P. Layne. High Speed, High Volume Laboratory Network for Infectious Diseases. Canada-California Infectious Diseases Collaboration Workshop. Los Angeles, CA. March 2 (2008).
- Scott P. Layne. New High-Throughput Laboratory for Molecular Surveillance of Influenza. Wadsworth Laboratory Presentation. Albany, NY. April 30 (2007).
- Scott P. Layne. New High-Throughput Laboratory for Molecular Surveillance of Influenza. National Foundation for Infectious Diseases: 10th Annual Conference on Vaccine Research. Baltimore, MD. May 2 (2007).
- Scott P. Layne. Melding Local, National and International Public Health Concerns. Los Angeles TEW/RAND Conference. Santa Monica, CA. May 9 (2008).
- Scott P. Layne. Identifying, Evaluating and Forecasting Infectious Diseases Threats. Institute for Advanced Studies 2008. Albuquerque, NM. May 22 (2008).
- Scott P. Layne. Near Real-Time Surveillance of Infectious Diseases. Google/SciFoo 2008. Mountain View, CA. August 8 (2008).
- Scott P. Layne. Center for Rapid Influenza Surveillance and Research. Indo-US Vaccine Action Program. Hyderabad, India. October 16 (2008).
- Scott P. Layne. Near Real-Time Surveillance of Infectious Diseases Globally. UCLA Global Health Workshop. Los Angeles, CA. October 23 (2008).
- Scott P. Layne, Michele Bergeron, Marc Madou. Speed in Diagnostics for Better Global Health and to Contain Emerging Threats in Infectious Diseases. Canada-California Infectious Diseases Collaboration. University Laval. Quebec, Canada. October 27 (2008).
- Scott P. Layne, Tony J. Beugelsdijk. Connecting Surveillance with the High-Throughput Laboratory. Scientific Advisory Board. Los Angeles, CA. December 11 (2008).
- Scott P. Layne, Tony Beugelsdijk. High-Throughput Laboratory Network Program. Centers for Disease Control and Prevention. Atlanta, GA. January 20-21 (2009).
- Alex Roth, Torsten Staab, Scott P. Layne. Processing of Mass Surveillance and Sample Information at a High-Throughput Laboratory. LabAutomation 2009. Palm Springs, CA January 27 (2009).
- Scott P. Layne, Tony Beugelsdijk. Overview of Genotyping System. HTLN Sequencing Pilot Summit for CDC/UCLA/LANL. Los Alamos, NM. March 11 (2009).
- Scott P. Layne. Connecting Surveillance with the High-Throughput Laboratory Network. CNSI Membership Luncheon. Los Angeles, CA. January 29 (2009).
- Scott P. Layne. How UCLA’s New Global BioLab Will Dramatically Improve Response Capabilities During a Pandemic. H1N1 Virus: What UCLA Experts Have to Say. Los Angeles, CA. May 13 (2009).
- Scott P. Layne. Dartmouth Course. Civilian Responses — Blue Team. Arlington, VA. November 30, 2016.
- Scott P. Layne. Homeland Security. Engineering Science 13, Dartmouth University. Hanover, NH. October 5, 2017.
- Scott P. Layne. Homeland Security. Engineering Science 13, Dartmouth University. Hanover, NH. October 11, 2018.
- Scott P. Layne. Virtual Medicine and Cybercare. Engineering Science 13, Dartmouth University. Hanover, NH. October 3, 2019.
- Scott P. Layne. All Things SARS-CoV-2. Engineering Science 13, Dartmouth University. Hanover, NH. April 15, 2020.
- Scott P. Layne. SARS-CoV-2 Diagnostics: Not a Slam Dunk. Providence Physicians. Santa Monica, CA. April 21, 2020.
- Scott P. Layne. SARS-CoV-2 Diagnostics: Not So Simple Yet. Providence Physicians. Santa Monica, CA. May 4, 2020.
White Papers
- Scott P. Layne. Identifying, Evaluating and Forecasting Infectious Diseases Threats. December 18, 2006.
- Scott P. Layne, Tony J. Beugelsdijk. High Speed, High Volume Laboratory Network for Infectious Diseases and Center for Rapid Influenza Surveillance and Research. September 22, 2008.
- Scott P. Layne. Wuhan Coronavirus Preparedness. January 22, 2020.
Committees, Peer Reviews, Special Appointments
- 1991 National Institute for Allergy and Infectious Diseases. Advisory Panel for Primate Challenge Viral Stocks. October 15 in Marco Island, FL.
- 1991 National Cancer Institute. Advisory Panel for AIDS Antiviral Drug Discovery. November 14 – 15 in Bethesda, MD.
- 1994 American Institute for Biological Science. Peer Review Panel for U.S. Army Medical Research and Development Command. May 19 in Washington, DC.
- 2001 UCLA Medical Center. Bioterrorism Task Force. Established in October and meets regularly.
- 2001 County of Los Angeles. Los Angeles County Task Force on Health Services Preparedness for Bioterrorism. Established by the Board of Supervisors in October and meets regularly.
- 2003 National Institute for Allergy and Infectious Diseases. Peer Review Panel for Food and Waterborne Diseases Integrated Research Network. February 26 – 27 in Washington, DC.
- 2003 National Institute for Allergy and Infectious Diseases. Peer Review Panel for Regional Centers of Excellence for Biodefense and Emerging Infectious Disease Research. May 28 and 30 in Washington, DC.
- 2007 National Institute for Allergy and Infectious Diseases. Chairperson, Special Emphasis Panel: Cooperative Research Partnerships for Influenza Product Development. January 24 – 25 and January 29 – 30 in Washington, DC.
- 2007 Member, Executive Committee. NIH/NIAID Centers of Excellence for Influenza Research and Surveillance.
- 2008 Member, National Biosurveillance Advisory Subcommittee under authority of Homeland Security Presidential Directive/HSPD-21. Appointment as Special Government Employee effective August 6, 2008 to May 3, 2010.
- 2010 American Institute for Biological Science. Peer Review Panel of the Infectious Disease Clinical Research Program for the Uniformed Services University of the Health Sciences. May 19 – 21 in Washington, DC.
- 2017 Infectious Diseases Society of America. IDSA Diagnostics Committee. Member. January 13, 2017 to January 12, 2018