Translational Research Departments

The clinicians and scientists at the John Wayne Cancer Institute work collaboratively to advance patient care. Our scientists investigate the mechanisms underlying a disease target of interest, and work directly with clinicians to translate lab-based discoveries into personalized treatment. This bench-to-beside approach fosters a truly beneficial experience for our patients, as they lead to novel findings and new directions for therapeutic interventions.

Specimen Repository View of the Translational Research Specimen Repository Neurosciences and Neurotherapeutics department researchers working together Doctor testing specimens in a controlled environment Two research scientists observing specimens

Translational Molecular Medicine

The Department of Translational Molecular Medicine is committed to the development and translational application of transcriptomic, genomic, and epigenomic biomarkers as diagnostic, prognostic and predictive tools in patients with solid tumors, particularly melanoma, breast cancer, prostate cancer, and gastrointestinal tract cancers.

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Translational Neurosciences & Neurotherapeutics

The department of Translational Neurosciences & Neurotherapeutics is accelerating the development of novel therapies for brain cancers and neurological disorders through drug innovations and precision medicine.

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Drug Discovery & Nanomedicine

The Drug Discovery and Nanomedicine Research Program fosters the development of novel, safe and effective therapeutics for both oral and intravenous delivery, to address the unmet disease needs in Oncology and the neurosciences.

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Cancer Epigenetics

Cancer Epigenetics Laboratory is focused on understanding the molecular determinants of tumor cell metastatic progression and drug resistance in cancer, particularly in aggressive forms of breast tumors and distant metastases. Specifically, we are interested in the epigenetic and epi-transcriptomic mechanisms that regulate gene expression programs in different tumor states, both at a regional level and in long-range chromatin interactions.

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Cancer Epigenetics Lab scientists

Computational Biology

The Computational Biology department is committed to understanding whole systems. The mission is to transform data into biological insights that will ultimately influence clinical practice. The focus is on applying various “omics” data to address translational questions.

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Philanthropy Sponsorship

The John Wayne Cancer Institute has a longstanding history of philanthropic support. Many of these gifts have helped fund groundbreaking cancer research.

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