Translating Advanced Cancer Research into Personalized, Passionate Treatment.

John Wayne Cancer Institute at Providence Saint John’s Health Center is a cancer research institute dedicated to the understanding, diagnosis, and innovative treatment of cancer in order to eliminate patient suffering and prolong survival.

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Go to centers of excellence

Dr. O’Day is world-renowned in the field of medical oncology and his leadership capabilities make him the ideal person to lead the cancer and research efforts on our campus and in our region.

Marcel Loh, Chief Executive of Providence Saint John’s Health Center

Clinical Trials

Clinical trials have always been an important part of John Wayne Cancer Institute. Our institute led the trials that established sentinel lymph node biopsy as the standard of care for melanoma and breast care and pioneered immunotherapy as treatment for melanoma. Today, our patients continue to have access to the latest treatments and trials. We are at the forefront of studying the biology of cancer as well as expanding treatment for those suffering world-wide.

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Attracting Patients from Around the World

As international leaders in cancer care, the John Wayne Cancer Institute attracts patients from all over the country and around the world. Seeing such a large number of patients, our team of experts bring a high level of experience to every aspect of your treatment. We’re with you from diagnosis through cure and have a team approach for better outcomes.

Meet our Experts

Surgical Oncology

Urology

Neurosurgery

Translational Molecular Medicine

Complex Surgical Oncology Fellowship

With a longstanding history of excellence in multidisciplinary cancer care and education, the John Wayne Cancer Institute continues to be a leader in training the next generation of leaders in the field of surgical oncology.

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Urologic Oncology Fellowship

The JWCI provides world class, multidisciplinary training in genitourinary malignancies and urologic oncology research with innovative and cutting edge technology.

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Neurosurgical Fellowship

This training program focuses on endonasal endoscopic and keyhole surgical approaches, neuro-endoscopy, pituitary tumor management and multimodality neuro-oncology treatments.

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Postdoctoral Lab-Based Translational Molecular Medicine Fellowship

As pioneers in translational studies on “liquid biopsies” involving circulating tumor cells in multiple types of solid tumors, the fellowship program also consists of studying epigenetic mechanisms regulating solid tumor as well as pharmacogenomics and immunogenomic based prediction of response to therapy.

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Latest News & Events

Publication

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

Dave S.B. Hoon, Ph.D., Professor and Director of Dept. of Translational Molecular Medicine and his team have published a new article in Cell Journal.

Scientific Presentations

Glioblastoma: Prognosis Treatment & Standard of Care

Glioblastoma is a cancer of the brain that’s difficult to treat because it invades the normal brain structure. Hear about the current and future treatment options for this deadly disease from Santosh Kesari M.D., Chair of Translational Neurosciences & Neurotherapeutics.

Publication

Early loss of Histone H2B monoubiquitylation alters chromatin accessibility and activates key immune pathways that facilitate progression of ovarian cancer

Dave S.B. Hoon, Ph.D., Professor and Director of Dept. of Translational Molecular Medicine in collaboration with the University of Pennsylvania have published a new article in Cancer Research Journal.

Translating Advanced Cancer Research into Personalized, Passionate Treatment.

Urology and Urologic Oncology

Melanoma, Skin and Soft Tissue Tumors

Endocrine Tumors and Disorders

Breast Surgery and Oncology

Minimally Invasive Chest Surgery and Thoracic Surgical Oncology

Gastrointestinal and Hepatobiliary Tumors

Gynecologic Oncology

Translational Lab Research

Brain Tumors & Neuroscience

Steven O’Day, MD, New Executive Director of the John Wayne Cancer Institute & Director of Providence Los Angeles Regional Research

Clinical Trials

Attracting Patients from Around the World

Fellowship Opportunities

Complex Surgical Oncology Fellowship

Urologic Oncology Fellowship

Neurosurgical Fellowship

Postdoctoral Lab-Based Translational Molecular Medicine Fellowship

Latest News & Events

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

Glioblastoma: Prognosis Treatment & Standard of Care

Early loss of Histone H2B monoubiquitylation alters chromatin accessibility and activates key immune pathways that facilitate progression of ovarian cancer