Translating Innovative Science into Compassionate, Patient-Centric Care

Saint John’s Cancer Institute is renowned for advancing therapeutics, translational science, and establishing standards of care. We foster robust fellowship programs, implement and initiate clinical trials, and collaborate with academic and industry partners worldwide.

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Innovation Starts Here

Saint John’s Cancer Institute (SJCI) is a pioneer in drug discovery, therapeutics, clinical trials, and research. SJCI established the Sentinel Lymph Node Biopsy under the late Dr. Donald L. Morton, which has become the standard of lymph node care for melanoma and breast cancer worldwide.

Today, our patients continue to have access to innovative treatments, therapeutics, and trials. We are at the forefront of understanding the biology of cancer as well as expanding treatment for under-served communities.

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Multi-cancer Early Detection (MCED) Testing

Providence is offering Multi-cancer Early Detection (MCED) testing to empower providers and the public with a blood test that can detect a shared cancer signal across 50+ types of cancer through a simple blood draw.

“Providence is committed to collaborations that provide individuals with the best evidence-based care including advancements like early cancer screenings that can improve patient outcomes.”

– Ora K. Gordon, MD, Regional Medical Director of Providence’s Clinical Genetics & Genomics Program

Providers are encouraged to request a test kit for eligible patients. See list of detectable cancers.

News: Providence Offers Multi-cancer Early Detection (MCED) Testing


Breakthroughs in Cancer Research: An Educational Event

Saint John’s Researchers Gather to Reveal the Future of Cancer: Doctors, Anton Bilchik, Jennifer Linehan, Ora Gordon, and Nicholas Schork, Ph.D., Adjunct Faculty at Saint John’s and Distinguished Professor of Quantitative Medicine at The Translational Genomics Research Institute (TGen), share critial insights

“We can set a precedent for the rest of the world on how clinical studies should be used to benefit patients in real-time and not 10 years after all the data has been aggregated in some way.”

– Nicholas Schork, Ph.D.

Learn more about how Saint John’s has become a remarkable contributor to global cancer science.

Blog & Videos (Preview 3:15, Full Program and Q&A 1:11:36): Breakthroughs in Cancer Research: An Educational Event

Educational Event - Future of Cancer Research

Why Are Clinical Trials Important?

Doctors, Kim Margolin, Przemyslaw Twardowski, Leland Foshag, Parvin Peddi, Santosh Kesari, and Emma Chacon, RN, Discuss the Impact of Clinical Trials and Advancement of Medical Science.

“…Patients own tumor DNA is used as the source of the antigenic material from which the vaccine is made and it acts to cause the body to make its own antigens and then sensitize the immune cells against those antigens.”

– Kim Margolin, MD

Learn more and listen to some of the principal investigators at Saint John’s Cancer Institute.

Blog, Video (16:45): International Clinical Trials Day: Hear from the experts in cutting-edge research

Clinical-Trials-Day-Saint-Johns-Cancer-Institute - Dr Kim Margolin

Open or Actively Recruiting Clinical Trials

Brain Cancer and Solid Tumors Clinical Trials

Principal Invenstigator: Dr. Akanksha Sharma: Learn more.

Breast Cancer: Precision Medicine

Principal Invenstigator: Dr. Parvin Peddi: Learn more.

Melanoma Cancer: Drug Trials:

Principal Investgator: Dr. Kim Margolin: Learn more.

Prostate Cancer: White Button Mushroom

Principal Invenstigator: Dr. Przemyslaw Twardowski: Learn more.

Current Trials

Search using key terms or filter by Centers of Excellence or by Lead Doctor. Learn more.

Saint John's Cancer Institute - Featured Clinical Trials

Bob Chooses Prostatectomy for Stage 2 Prostate Cancer

Expert Prostate Robotic Surgeon, Dr. Timothy Wilson, and Urologic Oncology Fellow, Dr. Joshua Gottlieb, Guided Bob’s Care at Saint John’s

“Every time I was here, it was just always a great experience. It was so simple. The folks in the office and and all the staff are just so swell.”

– Bob Tilly

Listen to Bob’s testimonial and how getting a second opinion changed his life.

Blog, Video (9:22): Prostate Cancer Thriver Chooses Robotic Assisted Prostatectomy with Timothy Wilson, MD

Dr. Timothy Wilson and Prostate Cancer Survivor Bobb Tilly

Breast Cancer Experts: An Empowering, 6-part Video Series on Breast Health

The Physicians at the Margie Petersen Breast Center Answer Challenging Questions Throughout the Month of October.

“Luckily for us, we have a great genetics team… It’s so easy to just pull them in. I love having them in my clinic.”

– Janie Grumley, MD

Watch all 6 highly informative videos here:

Blog, Videos: Breast Cancer Experts: An Empowering Video Series on Breast Health

Breast Experts Series - Saint John's Cancer Institute

Jackie Chooses Thyroidectomy for Thyroid Cancer

Dr. Melanie Goldfarb, Director of the Center for Endocrine Tumors and Disorders at Providence Saint John’s Health Center, provided the personalized care Jackie was looking for.

“It’s the scariest thing you can hear… the C-word.”

– Jackie Arechar

Learn more about Jackie’s story and how she knew she was in the right place to treat her thyroid cancer.

Blog, Video (12:58): A Mother of Two Diagnosed at 28 With Thyroid Cancer

Dr. Melanie Goldfarb and Jackie, thyroid cancer survivor, at Saint John's Health Center

A New Treatment That Was Worth the Wait

Thyroid Radiofrequency Ablation Shrinks 5.5 cm Tumor Over 90 Percent After Treatment.

“[Dr. Goldfarb] Your optimism and enthusiasm made me feel comfortable at a time of significant stress for me, and what can I say, your work is pretty good, and I’m living proof.”

– Scott Millward

Learn more about Scott’s decision to wait for a particular treatment and his unexpected outcome.

Blog, Video (9:30): Thyroid Radiofrequency Ablation Shrinks Benign Nodule Over 90 Percent After Treatment

Scott Millward - Treated at Saint John's Health Center

Care Excellence with a 5-star Rating

The Centers for Medicare and Medicaid Services (CMS) announced that Providence Saint John’s Health Center has earned a 5-star rating for providing quality and safe care to our community.

“This change highlighted the importance of a plan’s ability to provide members with continuous positive experiences, in addition to offering quality patient care that meets or exceeds industry standards.”


Learn more about the significance of the CMS, 5-star rating.

News: Providence Saint John’s Health Center Earns CMS 5-star Quality and Safety Rating

Saint Johns Heath Center Santa Monica CA

Saint John’s: A Legacy of Care Excellence

30 Major Healthcare Awards for 2022 and 2023

“All of these achievements reflect the outstanding care our caregivers and physicians provide to our patients each and every day, …providing leading-edge, award-winning care in a compassionate, community hospital setting. I am honored to share that this commitment to excellence has continued in our 80th year.”

– Michael Ricks, CEO, Saint John’s Health Cancer and Institute

Healthgrades awards include the Pulmonary Care Excellence Award (top 10% in the nation), Five-Star Ratings for Total Knee Replacement, Total Hip Replacement, as well as Treatment of Stroke, COPD, Pneumonia, Bowel Obstruction, and Sepsis. Several surgical awards for cancer were recognized by U.S. NEWS & World Report.

About Us, Awards: Saint John’s Health Center Awards

Saint Johns Health Center Awards

A Legacy of Research Excellence

Donald L. Morton, Surgical Oncologist best known for developing sentinel lymph node evaluation

“He was ahead of his peers in anticipating the genetics era of cancer research, for decades he carefully maintained archival specimen resource for correlative translational studies.”

– Laura Morton Rowe, Chief Human Resources Officer, Saint John’s Health Center

Learn more about the Donald L. Morton Complex General Surgical Oncology Fellowship.

OVERVIEW & VIDEO (18:43): Learn more about the Donald L. Morton Complex General Surgical Oncology Fellowship.

Donald L. Morton Complex General Surgical Oncology Fellowship - Saint John's Cancer Institute

Fellowship Programs

Breast Surgical Oncology
Surgical Oncology
Translational Molecular Medicine

Breast Surgical Oncology Fellowship

The Breast Surgical Oncology Fellowship at the Saint John’s Cancer Institute provides a diverse and comprehensive exposure to the multidisciplinary aspects of breast cancer care and benign breast disease over a one-year time period with a potential second year for continuation of clinical or basic science research.


Donald L. Morton Complex General Surgical Oncology Fellowship

With a longstanding history of excellence in multidisciplinary cancer care and research, the Saint John’s Cancer Institute continues its legacy in surgical oncology through the Donald L. Morton Complex General Surgical Oncology Fellowship.

Learn more about this fellowship

Neurosurgical Fellowship

This training program focuses on endonasal endoscopic and keyhole surgical approaches, neuro-endoscopy, pituitary tumor management and multimodality neuro-oncology treatments.

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Postdoctoral Lab-Based Translational Molecular Medicine Fellowship

As pioneers in translational studies on “liquid biopsies” involving circulating tumor cells in multiple types of solid tumors, the fellowship program also consists of studying epigenetic mechanisms regulating solid tumor as well as pharmacogenomics and immunogenomic based prediction of response to therapy.

Learn more about this fellowship

Urologic Oncology Fellowship

Providing world class, multidisciplinary training in genitourinary malignancies and urologic oncology research with innovative and cutting edge technology.

Learn more about this fellowship
Breast Oncology Fellowship - Saint John's Cancer Institute
Donal L Morton - Saint Johns Cancer Institute
neuroscience fellowship
translational molecular medicine
davinci Xi surgical robot

Saint John's Health Center
Saint John's Health Center Foundation
Pacific Neuroscience Institute
Associate of Breast and Prostate and Prostate Cancer Studies