Anatomic Pathology
Clinical and Laboratory Pathology
David Krasne, MD
During the 1990s, alongside researchers at the Saint John’s Cancer Institute including Drs. Donald Morton and Armando Giuliano, Dr. Krasne developed and published some of the seminal work on the pathologic techniques used to evaluate sentinel lymph nodes for breast cancer and melanoma; techniques which today remain the international standard of care in the evaluation of patients with these and certain other cancer types. Dr. Krasne has over 30 years’ experience evaluating tumors at the Cancer Institute and Saint John’s Health Center, and maintains disease specific expertise in many areas of tumor pathology.
As Medical Director of Saint John’s Laboratory since 1994, some of Dr. Krasne’s other professional interests include: how pathologists add value to patient care, modern laboratory techniques available to expedite best patient care decisions, development of systems-based approaches to diagnostic error prevention, and the education of Cancer Institute surgical oncology fellows in the spirit of shaping cancer surgeons of the future.
Education and Training
University of California, San Diego: B.A, Biology, 1981
Stanford University: Fellowship, Surgical and Oncologic Pathology, 1988
University of Southern California: Residency, Laboratory Medicine, 1990
Karolinska Institute, Stockholm: Fine Needle Aspiration Cytology, 1989
Mayo Clinic, Rochester: Genitourinary Pathology Sebbatical, 2013
Publications
Lombard CM, Tazelaar HD, Krasne DL: Pulmonary Eosinophilia in Coccidioidal Infection. Chest 91:734-736, 1987.
Krasne DL, Warnke RA, Weiss LM: Malignant Lymphoma Presenting as Pseudoepitheliomatous Hyperplasia: Report of Two Cases. American Journal of Surgical Pathology 12:835-842, 1988
Meyers BD, Sibley R, … Krasne DL, et.al.: The Long-Term Course of Cyclosporine-Associated Chronic Nephropathy. Kidney International 33:590-600, 1988.
McDougall R, Krasne DL, et.al.: Metastatic Malignant Struma Ovarii Presenting as Paraparesis from a Spinal Metastasis. Journal of Nuclear Medicine 30:5407-411, 1989.
Krasne DL, Naritoku W, Cosgrove M: Diagnosis of Syncytial (Lacunar Cell Predominant) Nodular Sclerosing Hodgkin’s Disease by Fine Needle Aspiration: Report of a Case. ACTA Cytologica, 37:418-422, 1993.
Giuliano AE, Dale PS, … Krasne DL, Morton DL. Improved Axillary Staging of Breast Cancer with Sentinel Lymphadenectomy. Ann Surgery 222: 394-401, 1995.
Turner RR, Ollila DW, Krasne DL, Giuliano AE: Histopathologic Validation of the Sentinel Lymph Node Hypothesis for Breast Carcinoma. Ann Surgery 226: 271-278, 1997.
Glass EC, Basinski JE, Krasne DL, Giuliano AE: Radiation Safety Considerations for Sentinel Node Techniques, Editorial. Annals of Surgical Oncology 6(1):10-11, 1999.
Turner RR, Giuliano AG, Hoon DS, Glass EC, Krasne DL: Pathologic Examination of the Sentinel Lymph Node for Breast Carcinoma: Invited Paper, World Journal of Surgery 25, 798-805, 2001
Haigh PI, Lucci A, Turner RR, Bostick PJ, Krasne DL, Stern SL, Morton DL: Carbon dye histologically confirms the identity of sentinel lymph nodes in cutaneous melanoma. Cancer 92:535-541, 2001.
Bilchik, A.J., Nora, D.t., Sobin, L.H., Turner, R.R., Trocha, S., Krasne, D., Morton, D.L.; Journal of Clinical Oncology. 2003 Feb15.
Jain M, Krasne DL, Singer FR, Giuliano AE. Recurrent primary hyperparathyroidism due to Type 1 parathyromatosis. Endocrine 2016 Oct 14; [Epub ahead of print].