Dr. Piening is trained in genetics, genomics and bioinformatics. Along with leading the Cancer Immuno-Genomics Lab at the Earle A. Chiles Research Institute, a Providence Center of Excellence for immuno-oncology and cellular therapy, he also serves as program director of Providence Genomics. There, he uses comprehensive genomic profiling to develop personalized treatment plans for people with advanced cancer. The laboratory is one of only a handful in the world that performs whole genome sequencing in a clinical context and is the dedicated clinical sequencing facility for Providence.
Dr. Piening oversees the Molecular Pathology Core facility at the Earle A. Chiles Research Institute. He also serves as an assistant professor for bioinformatics and medical education at the University of Washington and assistant professor of biology at Portland State University.
Cancer Immuno-Genomics Lab
At the Cancer Immuno-Genomics Lab, Dr. Piening and his team use sequencing, mass spectrometry and other technologies to gain new insights into human health and disease. A key focus of the lab is to develop multi-omic biomarkers to better predict how patients will respond to precision therapies and immunotherapies.
Using novel epigenomic, single cell and spatial approaches, the team seeks to comprehensively profile the tumor microenvironment (the tumor and its surrounding areas) to better understand why therapies succeed or fail. The team also applies these approaches for risk stratification across other clinical applications including organ transplantation failure, preterm birth and obesity/metabolic disease.
Cancer Immuno-Genomics Laboratory
Earle A. Chiles Research Institute
Providence Cancer Institute
4805 Northeast Glisan Street, Portland, OR 97213, US
https://www.providence.org/locations/or/earle-a-chiles-research-institute/piening