Current Research Topics Epigenetic and Epi-Transcriptomic Reprogramming Epigenetic alterations, which are chemical modifications to the genome that do notalter base composition, have emerged as powerful mechanisms to better understand, diagnose, classify and treat cancer. Epigenetic Classifiers for Precision Oncology The identification and characterization of disease-specific epigenetic alterations, particularly DNA methylation, continues to grow at a rapid pace, highlighting the important and numerous roles these modifications play in disease etiology and progression. RNA Splicing Regulation of Immune Response in Triple-Negative Breast Cancer Alternative splicing (AS) is a natural process which greatly contributes to the diversity of the human proteome, causing a single mRNA transcript to be spliced in various ways to generate functionally unique and diverse proteins.