The Saint John’s Cancer Institute Melanoma Center conducts landmark international research and clinical trials to identify new or recurrent melanoma at its earliest stages, predicts and monitors the response to systemic treatments, and develops active and passive immunotherapies for surgical and nonsurgical patients. Our dedicated clinical team, including surgical and medical oncologists, is committed to providing highly advanced care for all our patients with compassion, ensuring each patient can achieve the best possible outcome.
Sentinel Lymph Node Biopsy
Sentinel lymph node biopsy involves the removal of the first draining lymph node to evaluate if cancer has spread. This minimally invasive procedure helps determine the extent of melanoma and guides further treatment decisions. By identifying the sentinel lymph node, we can provide more accurate staging and reduce the need for extensive lymph node removal, minimizing potential side effects and improving patient recovery.
Click here to learn more about Sentinel lymph node biopsy.
Completion Node Dissection
Completion node dissection entails the removal of all the lymph nodes in a lymph node basin. This procedure is typically recommended if cancer cells are found in the sentinel lymph node. By removing additional lymph nodes, we aim to prevent the spread of melanoma and improve long-term outcomes. Our experienced surgical team ensures that patients receive the highest standard of care, with a focus on minimizing complications and promoting swift recovery.
Click here to learn more about completion node dissection.
Wide Local Excision
Wide local excision is a surgical treatment for primary melanoma where a margin of normal tissue is taken around the melanoma. This approach ensures that all cancerous cells are removed, reducing the risk of recurrence. Our skilled surgeons use advanced techniques to achieve optimal cosmetic results while maintaining the highest standards of oncologic safety. Patients can expect personalized care and support throughout their treatment journey.
Click here to learn more about wide local excision.
Chemotherapy
Chemotherapy is a systemic therapy that non-specifically kills rapidly dividing cells and is used for metastatic melanoma. While traditional chemotherapy has been less effective for melanoma, it remains an option for certain cases. Our team continuously evaluates the latest advancements in chemotherapy to provide the most effective treatments with the least side effects, ensuring our patients receive the best possible care.
Click here to learn more about chemotherapy.
Immunotherapy
Immunotherapy is a revolutionary and highly effective treatment that uses the body’s own immune system to attack cancer. By stimulating the immune response, immunotherapy can target and destroy melanoma cells more effectively. Our center offers a range of immunotherapy options, including checkpoint inhibitors like pembrolizumab and nivolumab, which have shown significant success in treating advanced melanoma1. We are dedicated to providing innovative treatments that offer hope and improved survival rates for our patients.
Click here to learn more about immunotherapy.
Targeted Therapy
Targeted therapy is a systemic treatment that targets specific genetic mutations on cancer cells. This precision medicine approach allows for more effective and less toxic treatments. At Saint John’s Cancer Institute, we offer targeted therapies such as vemurafenib, dabrafenib, and trametinib, which have been proven to be effective in treating melanoma with specific genetic mutations2. Our personalized treatment plans ensure that each patient receives the most appropriate and effective therapy for their condition.
Click here to learn more about targeted therapy.
Radiation Therapy
Radiation therapy can help reduce the risk of melanoma coming back after surgery or relieve symptoms in advanced cases. By using high-energy rays to target cancer cells, radiation therapy can effectively control the spread of melanoma. Our state-of-the-art radiation oncology department provides precise and tailored treatments to maximize effectiveness while minimizing side effects. Patients receive comprehensive care and support throughout their radiation therapy journey.
Clinical Trials
The current standard treatment for metastatic melanoma is rapidly evolving. In the past, chemotherapy such as dacarbazine was used, but had relatively limited effectiveness. In recent years, several new medications have been approved for melanoma treatment. These include targeted therapies (vemurafenib, dabrafenib, trametinib) and immunotherapies (ipilimumab, pembrolizumab)3. Other drugs are likely to be approved in the near future.
Clinical trials are often the best option for patients with metastatic melanoma. Investigators at Saint John’s Cancer Institute strive to develop the latest melanoma treatment approaches that have the greatest chance of success. Determining the right treatment for any individual requires careful consideration of both the patient’s situation and preferences as well as the opportunities for treatments available as standards or in a clinical trial. Comprehensive consideration of all skin cancer treatment options in a multidisciplinary context will enable a patient to develop a long-term treatment strategy that will give them the best opportunity for treatment success and optimal quality of life.
If you have questions regarding the different kinds of treatments for melanoma, please call today or click here to schedule an appointment or for an expert second opinion.
