Metastatic Melanoma is a Challenging Malignancy to Treat Historically. Until 2011, only dacarbazine and high-dose interleukin 2 (IL-2) were approved for the treatment of metastatic disease. These therapies are not active in melanoma and with the advances in immunotherapy and targeted treatment, chemotherapy is not used as frequently.

The Process of Chemotherapy

Chemotherapy uses drugs that kill cancer cells. The drugs are usually injected into a vein or taken by mouth as a pill.