Over time, many of your symptoms should go away; weight loss, bruising, and face shape generally happen first. However, your body needs time to re-regulate itself, so these changes are not going to happen overnight. For instance, if you have newly diagnosed diabetes and/or high blood pressure that was caused by Cushing’s, they will likely improve over time and for a good number of patients, you will return to your pre-CUshing’s state. However, if they have been long-standing, there may be some lasting effects and therefore close monitoring is needed. Additionally, some autoimmune disorders may have been suppressed by the increased cortisol levels and so may appear/reappear after normalization of cortisol levels.
You will have regular follow-up with your endocrinologist to help manage your medications and monitor your blood tests. You should also return to your surgeon for a post-op visit 2 weeks after surgery as well as at one year. You will likely have yearly blood tests due to the very small chance of recurrence in the other adrenal gland. Cardiovascular, bone, and glucose monitoring should be performed on a regular basis.