Osteoporosis is a common metabolic bone disease in which bone density decreases and bones become more fragile, increasing the risk of fractures in the spine, hip, and wrist. Because the condition often progresses silently, many people are unaware they have osteoporosis until a fracture occurs.

Saint John's Health Center in Santa Monica, CA
Saint John’s Health Center in Santa Monica, CA

At the Saint John’s Health Center our specialists at the Center for Endocrine Tumors and Disorders, provide comprehensive evaluation, bone density testing, fracture‑risk assessment, and develop personalized treatment plans to protect long‑term bone health.

Osteoporosis Causes and Risk Factors

Osteoporosis develops due to a combination of biological, hormonal, and lifestyle factors. Understanding these contributors helps guide prevention and treatment strategies. Some causes are unavoidable, such as aging, while others—like nutritional deficiencies or inactivity—can be modified to support bone health.

Common Risk Factors

Several well‑established factors increase the likelihood of developing osteoporosis. These include aging, hormonal changes such as menopause or low testosterone, family history, and vitamin D or calcium deficiency. Endocrine disorders such as parathyroid disease or thyroid conditions can also contribute to bone loss.

Healthy bone compared to osteoporosis.
Properly evaluating hormone changes helps us provide more effective treatment plans for osteoperosis.
  • Aging and natural bone density decline
  • Hormonal changes (menopause, low testosterone)
  • Family history of osteoporosis
  • Vitamin D or calcium deficiency
  • Long‑term steroid use
  • Sedentary lifestyle
  • Thyroid or parathyroid disorders
  • Smoking or heavy alcohol consumption

Medical Conditions That Increase Risk

Certain endocrine and metabolic disorders can accelerate bone loss and increase fracture risk. Conditions such as hyperparathyroidism, chronic kidney disease, gastrointestinal malabsorption, and thyroid disease may contribute to osteoporosis. Our genetic counseling team can also evaluate hereditary factors that may influence bone health.

How Osteoporosis Is Diagnosed

Accurate diagnosis is essential for determining the severity of bone loss and guiding treatment. Our team uses advanced imaging, laboratory testing, and fracture‑risk assessment tools to evaluate bone health and identify underlying causes. Early diagnosis allows for timely intervention that can significantly reduce fracture risk.

Bone Density (DEXA) Scan

Bone Density (DEXA) Scan of the hip and spine
Bone density evaluation of the hip and spine can help determine the extent of bone loss.

A DEXA scan is the gold‑standard test for diagnosing osteoporosis. This painless imaging study measures bone mineral density (BMD) in the hip and spine, providing a clear picture of bone strength. Learn more about our endocrine imaging capabilities through the Endocrine Surgery Program, which works closely with our diagnostic team.

Laboratory Testing

Blood and urine tests help identify metabolic or endocrine causes of bone loss. These tests evaluate calcium levels, vitamin D status, thyroid function, parathyroid hormone (PTH), and markers of bone turnover. Identifying endocrine contributors—such as parathyroid disease—helps tailor treatment to each patient’s needs.

Other Bone Conditions

Patients may also suffer from bone-related conditions including Paget’s Bone Disease, Fibrous Dysplasia, and Bone Metastasis from Cancer. These conditions may affect one or more bones in the body. See Other Bone Disorders.

Osteoporosis Treatment Options at Saint John’s

Treatment for osteoporosis focuses on strengthening bones, reducing fracture risk, and addressing underlying causes of bone loss. Our team develops personalized treatment plans based on bone density results, laboratory findings, age, fracture history, and overall health. Many patients benefit from a combination of lifestyle changes, medication, and targeted endocrine care.

Treatment of Underlying Conditions

Evaluation of osteoporosis conditions
Our endocrine specialists can effectively evaluate osteoporosis conditions and coordinate your care accordingly.

When osteoporosis is caused by endocrine disorders such as hyperparathyroidism or thyroid disease, treating the underlying condition can significantly improve bone health. Management may include correcting hormone imbalances, addressing overactive glands, or stabilizing metabolic factors that contribute to bone loss. Our specialists evaluate each patient for contributing endocrine issues and coordinate care accordingly. Learn more about related endocrine conditions, including parathyroid disease and thyroid cancer.

Why Choose Saint John’s for Osteoporosis Care?

At the Saint John’s Cancer Institute, our endocrine specialists provide expert evaluation and treatment for osteoporosis and metabolic bone disorders. We combine advanced diagnostic tools with personalized care to help patients strengthen their bones and reduce fracture risk. Our multidisciplinary approach ensures comprehensive support for every aspect of bone health.

Our Expertise

Our team includes experienced endocrinologists who specialize in metabolic bone disease and endocrine‑related bone conditions. We offer advanced diagnostic imaging, laboratory evaluation, and individualized treatment plans tailored to each patient’s needs. Collaboration with orthopedics, nutrition, and other specialties ensures well‑rounded care. Learn more about our Endocrine Tumors & Disorders Center.

Endocrine team at Saint John's Health Center

Rose Lin, MD, and Sarah Rettinger, MD, – Endocrinologists at Saint John’s Health Center in Santa Monica, CA.

If you have questions regarding osteoperosis symptoms, or treatment, please call today. Click here to request an appointment.